QUOTE
Having everyone in a town rally around you, or turn against you, is more the sort of thing that would happen as part of a quest. The individual NPCs decide how they feel about you and how they'll treat you on their own, not just because of the town they happen to be in. But we do have quests where, for example, you have to go around and try to muster soldiers from each town to come and fight with you in a big battle, and if you've managed to get soldiers in that town mad at you, they simply won't come.
http://www.pixelefx.com/index.php?page=int...&id=oblivion-pc
Calling the population of Imperial City into a war sounds fun...

If you're a member of the Mages and Fighters guilds, I'm guessing they're gonna fight for you.